{"id":1105,"date":"2023-03-03T09:35:07","date_gmt":"2023-03-03T01:35:07","guid":{"rendered":"https:\/\/app.lemaidi888.com\/?p=1105"},"modified":"2023-03-03T09:35:07","modified_gmt":"2023-03-03T01:35:07","slug":"%e9%85%ae%e5%ba%b7%e5%94%91-65277-42-1-%e7%91%9e%e5%a8%81%e5%b0%94%e7%94%9f%e7%89%a9%e7%a7%91%e6%8a%80","status":"publish","type":"post","link":"https:\/\/app.lemaidi888.com\/?p=1105","title":{"rendered":"\u916e\u5eb7\u5511 | 65277-42-1 | \u745e\u5a01\u5c14\u751f\u7269\u79d1\u6280"},"content":{"rendered":"\n<figure class=\"wp-block-table\"><table><tbody><tr><td>\u4e2d\u6587\u540d<\/td><td>\u916e\u5eb7\u5511<\/td><\/tr><tr><td>\u4e2d\u6587\u540c\u4e49<\/td><td>\u916e\u5eb7\u5511\u4e2d\u6587\u540d\u916e\u5eb7\u5511\u4e2d\u6587\u540c\u4e49 \u987a-1-\u4e59\u9170\u57fa-4-[4-[[2-(2,4-\u4e8c\u6c2f\u82ef\u57fa)-2-(1H-\u54aa\u5511-1-\u57fa\u7532\u57fa)-1,3-\u4e8c\u6c27\u620a\u73af-4-\u57fa]\u7532\u6c27\u57fa]\u82ef\u57fa]\u54cc\u55ea;\u916e\u5eb7\u5511\u539f\u6599\u836f\u751f\u4ea7\u5382\u5bb6;\u916e\u5eb7\u5511 1-\u4e59\u9170\u57fa-4[4-[2-(2,4-\u4e8c\u6c2f\u82ef\u57fa)-2(1H-\u54aa\u5511-1-\u7532\u57fa)-1,3\u4e8c\u6c27\u620a\u73af-4-\u7532\u6c27\u57fa]\u82ef\u57fa]-\u54cc\u55ea;\u916e\u5eb7\u5511(\u916e\u4ea2\u5511\u3001\u9176\u5eb7\u7075);\u916e\u5eb7\u5511\/\u916e\u4ea2\u5511\/\u987a-1-\u4e59\u9170\u57fa-4-[4-[[2-(2,4-\u4e8c\u6c2f\u82ef\u57fa)-2-(1H-\u54aa\u5511-1-\u57fa\u7532\u57fa)-1,3-\u4e8c\u6c27\u620a\u73af-4-\u57fa]\u7532\u6c27\u57fa]\u82ef\u57fa]\u54cc\u55ea;\u916e\u5eb7\u5511\u6eb6\u6db2, 100PPM;\u916e\u5eb7\u5511\u539f\u6599\u836f\u5382\u5bb6\u73b0\u8d27;\u6e56\u5317\u916e\u5eb7\u5511\u539f\u6599\u836f<\/td><\/tr><tr><td>\u82f1\u6587\u540d<\/td><td>Ketoconazole<\/td><\/tr><tr><td>\u82f1\u6587\u540c\u4e49<\/td><td>,3-dioxolan-4-yl)methoxy)phenyl)-,cis-;fungarest;fungoral;ketoconazol;ketoderm;ketoisdin;kw-1414;nizoral<\/td><\/tr><tr><td>CAS<\/td><td><strong>65277-42-1<\/strong><\/td><\/tr><tr><td>\u5206\u5b50\u5f0f<\/td><td>C26H28Cl2N4O4<\/td><\/tr><tr><td>\u5206\u5b50\u91cf<\/td><td>531.43<\/td><\/tr><tr><td>EINECS<\/td><td>265-667-4<\/td><\/tr><tr><td>\u7ed3\u6784\u5f0f<\/td><td><img decoding=\"async\" alt=\"\u916e\u5eb7\u5511\" src=\"https:\/\/upload.ruiweier.cn\/images\/cas\/65277-42-1.gif\"><\/td><\/tr><tr><td>\u6027\u8d28<\/td><\/tr><tr><td>\u7194\u70b9<\/td><td>146\u00b0C<\/td><\/tr><tr><td>\u6cb8\u70b9<\/td><td>753.4\u00b160.0 \u00b0C(Predicted)<\/td><\/tr><tr><td>\u5bc6\u5ea6<\/td><td>1.4046 (rough estimate)<\/td><\/tr><tr><td>\u6298\u5c04\u7387<\/td><td>-10.5 \u00b0 (C=0.4, CHCl3)<\/td><\/tr><tr><td>\u95ea\u70b9<\/td><td>9\u2103<\/td><\/tr><tr><td>\u50a8\u5b58\u6761\u4ef6<\/td><td>2-8\u00b0C<\/td><\/tr><tr><td>\u6eb6\u89e3\u5ea6<\/td><td>methanol: soluble50mg\/mL<\/td><\/tr><tr><td>\u9178\u5ea6\u7cfb\u6570(pKa)<\/td><td>pKa 3.25\/6.22(H2O,t =25,I=0.025) (Uncertain)<\/td><\/tr><tr><td>\u5f62\u6001<\/td><td>Off-white solid<\/td><\/tr><tr><td>\u989c\u8272<\/td><td>white to light yellow<\/td><\/tr><tr><td>\u65cb\u5149\u6027 (optical activity)<\/td><td>[\u03b1]20\/D -1 to 1\u00b0, c = 4 in methanol<\/td><\/tr><tr><td>\u6c34\u6eb6\u89e3\u6027<\/td><td>Soluble in DMSO, ethanol, chloroform, water, and methanol.<\/td><\/tr><tr><td>Merck<\/td><td>14,5302<\/td><\/tr><tr><td>InChIKey<\/td><td>XMAYWYJOQHXEEK-OZXSUGGESA-N<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u672c\u516c\u53f8\u7684\u6240\u6709\u4ea7\u54c1\u4ec5\u7528\u4e8e\u79d1\u5b66\u7814\u7a76\u6216\u8005\u5de5\u4e1a\u5e94\u7528\u7b49\u975e\u533b\u7597\u76ee\u7684\uff0c\u4e0d\u53ef\u7528\u4e8e\u4eba\u7c7b\u6216\u52a8\u7269\u7684\u4e34\u5e8a\u8bca\u65ad\u6216\u6cbb\u7597\uff0c\u975e\u836f\u7528\uff0c\u975e\u98df\u7528\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4e2d\u6587\u540d \u916e\u5eb7\u5511 \u4e2d\u6587\u540c\u4e49 \u916e\u5eb7\u5511\u4e2d\u6587\u540d\u916e\u5eb7\u5511\u4e2d\u6587\u540c\u4e49 \u987a-1-\u4e59\u9170\u57fa-4-[4-[[2-(2,4-\u4e8c\u6c2f\u82ef\u57fa)- [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1105","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/1105","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1105"}],"version-history":[{"count":1,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/1105\/revisions"}],"predecessor-version":[{"id":1106,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/1105\/revisions\/1106"}],"wp:attachment":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1105"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1105"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1105"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}