{"id":1592,"date":"2023-05-10T09:31:53","date_gmt":"2023-05-10T01:31:53","guid":{"rendered":"https:\/\/app.lemaidi888.com\/?p=1592"},"modified":"2023-05-10T09:31:53","modified_gmt":"2023-05-10T01:31:53","slug":"%e6%9b%b2%e7%be%8e%e6%9b%bf%e5%b0%bc-871700-17-3-%e7%91%9e%e5%a8%81%e5%b0%94%e7%94%9f%e7%89%a9%e7%a7%91%e6%8a%80","status":"publish","type":"post","link":"https:\/\/app.lemaidi888.com\/?p=1592","title":{"rendered":"\u66f2\u7f8e\u66ff\u5c3c | 871700-17-3 | \u745e\u5a01\u5c14\u751f\u7269\u79d1\u6280"},"content":{"rendered":"\n<figure class=\"wp-block-table\"><table><tbody><tr><td>\u4e2d\u6587\u540d<\/td><td>\u66f2\u7f8e\u66ff\u5c3c<\/td><\/tr><tr><td>\u4e2d\u6587\u540c\u4e49<\/td><td>\u66f2\u7f8e\u66ff\u5c3c;\u66f2\u7f8e\u66ff\u5c3c\u80f6\u56ca;\u66f2\u7f8e\u66ff\u5c3c, \u4e00\u79cdMEK1\/2 \u6291\u5236\u5242;N-[3-[3-\u73af\u4e19\u57fa-5-[(2-\u6c1f-4-\u7898\u82ef\u57fa)\u6c28\u57fa]-3,4,6,7-\u56db\u6c22-6,8-\u4e8c\u7532\u57fa-2,4,7-\u4e09\u6c27\u4ee3\u5421\u5576\u5e76[4,3-D]\u5627\u5576-1(2H)-\u57fa]\u82ef\u57fa]\u4e59\u9170\u80fa;\u66f2\u7f8e\u66ff\u5c3c\u6e38\u79bb\u78b1;\u66f2\u7f8e\u66ff\u5c3c\u3001GSK1120212;\u66f2\u7f8e\u66ff\u5c3c1;MEK\u6291\u5236\u5242(TRAMETINIB)<\/td><\/tr><tr><td>\u82f1\u6587\u540d<\/td><td>Trametinib<\/td><\/tr><tr><td>\u82f1\u6587\u540c\u4e49<\/td><td>N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide GSK-1120212;Trametinib free base;Mekinist trametinib;Trametinib (GSK1120212,JTP 74057);Trametinib, &gt;=98%;CS-30;Trametinib Impurity;100836<\/td><\/tr><tr><td>CAS<\/td><td><strong>871700-17-3<\/strong><\/td><\/tr><tr><td>\u5206\u5b50\u5f0f<\/td><td>C26H23FIN5O4<\/td><\/tr><tr><td>\u5206\u5b50\u91cf<\/td><td>615.39<\/td><\/tr><tr><td>EINECS<\/td><td><\/td><\/tr><tr><td>\u7ed3\u6784\u5f0f<\/td><td><img decoding=\"async\" alt=\"\u66f2\u7f8e\u66ff\u5c3c\" src=\"https:\/\/upload.ruiweier.cn\/images\/cas\/871700-17-3.gif\"><\/td><\/tr><tr><td colspan=\"2\">\u6027\u8d28<\/td><\/tr><tr><td>\u7194\u70b9<\/td><td>300-301 \u00b0C<\/td><\/tr><tr><td>\u5bc6\u5ea6<\/td><td>1.74<\/td><\/tr><tr><td>\u5f62\u6001<\/td><td>White solid.<\/td><\/tr><tr><td>\u9178\u5ea6\u7cfb\u6570(pKa)<\/td><td>14.76\u00b10.70(Predicted)<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>\u4e2d\u6587\u540d \u66f2\u7f8e\u66ff\u5c3c \u4e2d\u6587\u540c\u4e49 \u66f2\u7f8e\u66ff\u5c3c;\u66f2\u7f8e\u66ff\u5c3c\u80f6\u56ca;\u66f2\u7f8e\u66ff\u5c3c, \u4e00\u79cdMEK1\/2 \u6291\u5236\u5242;N-[3-[3-\u73af\u4e19 [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1592","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/1592","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1592"}],"version-history":[{"count":1,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/1592\/revisions"}],"predecessor-version":[{"id":1593,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/1592\/revisions\/1593"}],"wp:attachment":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1592"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1592"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1592"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}