{"id":2947,"date":"2023-06-25T09:19:37","date_gmt":"2023-06-25T01:19:37","guid":{"rendered":"https:\/\/app.lemaidi888.com\/?p=2947"},"modified":"2023-06-25T09:19:38","modified_gmt":"2023-06-25T01:19:38","slug":"%e7%94%b2%e6%b0%a8%e8%9d%b6%e5%91%a4-59-05-2-%e7%91%9e%e5%a8%81%e5%b0%94%e7%94%9f%e7%89%a9%e7%a7%91%e6%8a%80-2","status":"publish","type":"post","link":"https:\/\/app.lemaidi888.com\/?p=2947","title":{"rendered":"\u7532\u6c28\u8776\u5464 | 59-05-2 | \u745e\u5a01\u5c14\u751f\u7269\u79d1\u6280"},"content":{"rendered":"\n<p>\u4e2d\u6587\u540d\u7532\u6c28\u8776\u5464<\/p>\n\n\n\n<p>\u4e2d\u6587\u540c\u4e49METHOTREXATE \u7532\u6c28\u8776\u5464;\u80fa\u7532\u558b\u5464\u6c34\u5408\u7269;\u7532\u6c28\u8776\u5464\u3001\u7532\u6c28\u8776\u5464\u6c34\u5408\u7269;\u7532\u6c28\u8776\u5464 \u56db\u5ddd\u5382\u5bb6;\u6c28\u7532\u8776\u5464\/\u7532\u6c28\u8776\u5464\/\u7532\u6c28\u57fa\u53f6\u9178\/\u6c28\u7532\u53f6\u9178\/\u5bf9-[(2,4-\u4e8c\u6c28\u57fa\u558b\u5576-6)-N-\u7532\u57fa\u7532\u6c28\u57fa]\u82ef\u7532\u9170\u8c37\u6c28\u9178\/\u4e8c\u6c34\u5408\u6c28\u7532\u560c\u5464\/(+)\u6c28\u7532\u8776\u5464\/N-[4-[[(2,4-\u4e8c\u6c28\u57fa-6-\u8776\u5576)\u7532\u57fa]\u7532\u6c28\u57fa]\u82ef\u7532\u9170]-L-\u8c37\u6c28\u9178;CAS:59-05-2\u6216133073-73-1;\u7532\u6c28\u8776\u5464,\u4e8c\u6c34\u5408 5G;\u7532\u6c28\u8776\u5464\u539f\u6599\u836f<\/p>\n\n\n\n<p>\u82f1\u6587\u540dMethotrexate<\/p>\n\n\n\n<p>\u82f1\u6587\u540c\u4e49METHOTREXATEFORINJECTION;sodium 4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]am ino]-5-hydroxy-5-oxo-pentanoate;METHOTREXATE(N-(4-(((2,4-DIAMINO-6-PTERIDINYL)METHYLAMINO)BENZOYL)-L-GLUTAMICACID);4-Amino-N10-methylfolic acid;Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, L-(+)- (8CI);L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- (9CI);L-Methotrexate;Methotrexat-Ebewe<\/p>\n\n\n\n<p>CAS<strong>59-05-2<\/strong><\/p>\n\n\n\n<p>\u5206\u5b50\u5f0fC20H22N8O5<\/p>\n\n\n\n<p>\u5206\u5b50\u91cf454.44<\/p>\n\n\n\n<p>EINECS200-413-8<\/p>\n\n\n\n<p>\u7ed3\u6784\u5f0f<img decoding=\"async\" src=\"https:\/\/upload.ruiweier.cn\/images\/cas\/59-05-2.gif\"><\/p>\n\n\n\n<p>\u6027\u8d28<\/p>\n\n\n\n<p>\u7194\u70b9195\u00b0C<\/p>\n\n\n\n<p>\u6bd4\u65cb\u5149\u5ea6+17\uff5e+24\u00b0(D\/20\u2103)(c=1,Na2CO3 soln.)(calculated on the dehydrous basis)<\/p>\n\n\n\n<p>\u6cb8\u70b9561.26\u00b0C (rough estimate)<\/p>\n\n\n\n<p>\u5bc6\u5ea61.4080 (rough estimate)<\/p>\n\n\n\n<p>\u6298\u5c04\u73871.6910 (estimate)<\/p>\n\n\n\n<p>\u95ea\u70b911\u2103<\/p>\n\n\n\n<p>\u50a8\u5b58\u6761\u4ef6\u221220\u00b0C<\/p>\n\n\n\n<p>\u6eb6\u89e3\u5ea6H2O: insoluble<\/p>\n\n\n\n<p>\u5f62\u6001powder<\/p>\n\n\n\n<p>\u9178\u5ea6\u7cfb\u6570(pKa)pKa 3.04\/4.99(H2O,t =25,I=0.0025) (Uncertain)<\/p>\n\n\n\n<p>\u6c34\u6eb6\u89e3\u6027Insoluble. &lt;0.1 g\/100 mL at 19 \u00baC<\/p>\n\n\n\n<p>\u654f\u611f\u6027Light Sensitive &amp; Hygroscopic<\/p>\n\n\n\n<p>Merck14,5985<\/p>\n\n\n\n<p>BRN70669<\/p>\n\n\n\n<p>\u7a33\u5b9a\u6027Stable, but light sensitive and hygroscopic. Incompatible with strong acids, strong oxidizing agents. Store at -15C or below.<\/p>\n\n\n\n<p>InChIKeyFBOZXECLQNJBKD-ZDUSSCGKSA-N<\/p>\n\n\n\n<p>(IARC)\u81f4\u764c\u7269\u5206\u7c7b3 (Vol. 26, Sup 7) 1987<\/p>\n\n\n\n<p>NIST\u5316\u5b66\u7269\u8d28\u4fe1\u606fMethotrexate(59-05-2)<\/p>\n\n\n\n<p>EPA\u5316\u5b66\u7269\u8d28\u4fe1\u606fMethotrexate (59-05-2)<\/p>\n\n\n\n<p>word \u5bfc\u51fa<\/p>\n\n\n\n<p>PDF<\/p>\n\n\n\n<p>Word<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4e2d\u6587\u540d\u7532\u6c28\u8776\u5464 \u4e2d\u6587\u540c\u4e49METHOTREXATE \u7532\u6c28\u8776\u5464;\u80fa\u7532\u558b\u5464\u6c34\u5408\u7269;\u7532\u6c28\u8776\u5464\u3001\u7532\u6c28\u8776\u5464\u6c34\u5408\u7269;\u7532\u6c28\u8776\u5464 [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2947","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/2947","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2947"}],"version-history":[{"count":1,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/2947\/revisions"}],"predecessor-version":[{"id":2948,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/2947\/revisions\/2948"}],"wp:attachment":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2947"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2947"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2947"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}