{"id":3416,"date":"2023-09-05T10:17:18","date_gmt":"2023-09-05T02:17:18","guid":{"rendered":"https:\/\/app.lemaidi888.com\/?p=3416"},"modified":"2023-09-05T10:17:19","modified_gmt":"2023-09-05T02:17:19","slug":"%e9%98%bf%e7%91%9e%e5%90%a1%e5%9d%a6%e4%b8%a8170729-80-3%e4%b8%a8%e7%91%9e%e5%a8%81%e5%b0%94%e7%94%9f%e7%89%a9%e7%a7%91%e6%8a%80","status":"publish","type":"post","link":"https:\/\/app.lemaidi888.com\/?p=3416","title":{"rendered":"\u963f\u745e\u5421\u5766\u4e28170729-80-3\u4e28\u745e\u5a01\u5c14\u751f\u7269\u79d1\u6280"},"content":{"rendered":"\n<figure class=\"wp-block-table\"><table><tbody><tr><td>\u4e2d\u6587\u540d<\/td><td>\u963f\u745e\u5421\u5766<\/td><\/tr><tr><td>\u4e2d\u6587\u540c\u4e49<\/td><td>5-[2(R)-[1(R)-[3,5-\u4e8c(\u4e09\u6c1f\u7532\u57fa)\u82ef\u57fa]\u4e59\u6c27\u57fa]-3(S)-(4-\u6c1f\u82ef\u57fa)\u5417\u5549-4-\u57fa\u7532\u57fa]-3,4-\u4e8c\u6c22-2H-1,2,4-\u4e09\u5511-3-\u916e;\u963f\u745e\u5339\u5766(\u963f\u745e\u5421\u5766);APREPITANT\u963f\u745e\u5421\u5766;\u4e2d\u95f4\u4f531(\u5373\u963f\u745e\u5339\u5766);\u963f\u745e\u5339\u5766APREPITANT;FS-\u798f\u6c99\u5421\u5766\u4e2d\u95f4\u4f538;5-[2(R)-[1(R)-[3,5-\u4e8c(\u4e09\u6c1f\u7532\u57fa)\u82ef\u57fa]\u4e59\u6c27\u57fa]-3(S)-(4-\u6c1f\u82ef\u57fa)\u5417\u5549-4-\u57fa\u7532\u57fa]-3,4-\u4e8c\u6c22;\u963f\u745e\u5339\u5766 (API)<\/td><\/tr><tr><td>\u82f1\u6587\u540d<\/td><td>Aprepitant<\/td><\/tr><tr><td>\u82f1\u6587\u540c\u4e49<\/td><td>CS-274;Aprepitant (MK-0869, L-754030);5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one;Emend;MK-0869;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one, Emend;Aprepitant(MK-0869)<\/td><\/tr><tr><td>CAS<\/td><td><strong>170729-80-3<\/strong><\/td><\/tr><tr><td>\u5206\u5b50\u5f0f<\/td><td>C23H21F7N4O3<\/td><\/tr><tr><td>\u5206\u5b50\u91cf<\/td><td>534.43<\/td><\/tr><tr><td>EINECS<\/td><td>677-636-6<\/td><\/tr><tr><td>\u7ed3\u6784\u5f0f<\/td><td><img decoding=\"async\" alt=\"\u963f\u745e\u5421\u5766\" src=\"https:\/\/upload.ruiweier.cn\/images\/cas\/170729-80-3.gif\"><\/td><\/tr><tr><td colspan=\"2\">\u6027\u8d28<\/td><\/tr><tr><td>\u7194\u70b9<\/td><td>244-246\u00b0C<\/td><\/tr><tr><td>\u6bd4\u65cb\u5149\u5ea6<\/td><td>D25 +69\u00b0 (c = 1.00 in methanol)<\/td><\/tr><tr><td>\u5bc6\u5ea6<\/td><td>1.51\u00b10.1 g\/cm3(Predicted)<\/td><\/tr><tr><td>\u50a8\u5b58\u6761\u4ef6<\/td><td>-20\u00b0C Freezer<\/td><\/tr><tr><td>\u5f62\u6001<\/td><td>powder<\/td><\/tr><tr><td>\u9178\u5ea6\u7cfb\u6570(pKa)<\/td><td>8.06\u00b10.20(Predicted)<\/td><\/tr><tr><td>\u989c\u8272<\/td><td>white to beige<\/td><\/tr><tr><td>\u65cb\u5149\u6027 (optical activity)<\/td><td>[\u03b1]\/D +61 to +71\u00b0, c = 1.0 in methanol<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>\u4e2d\u6587\u540d \u963f\u745e\u5421\u5766 \u4e2d\u6587\u540c\u4e49 5-[2(R)-[1(R)-[3,5-\u4e8c(\u4e09\u6c1f\u7532\u57fa)\u82ef\u57fa]\u4e59\u6c27\u57fa]-3(S)-(4 [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3416","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/3416","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3416"}],"version-history":[{"count":1,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/3416\/revisions"}],"predecessor-version":[{"id":3417,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/3416\/revisions\/3417"}],"wp:attachment":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3416"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3416"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3416"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}