{"id":589,"date":"2022-12-05T14:22:18","date_gmt":"2022-12-05T06:22:18","guid":{"rendered":"https:\/\/app.lemaidi888.com\/?p=589"},"modified":"2022-12-05T14:22:18","modified_gmt":"2022-12-05T06:22:18","slug":"%e5%bc%82%e7%bb%b4a%e9%85%b8-4759-48-2-%e7%91%9e%e5%a8%81%e5%b0%94%e7%94%9f%e7%89%a9%e7%a7%91%e6%8a%80","status":"publish","type":"post","link":"https:\/\/app.lemaidi888.com\/?p=589","title":{"rendered":"\u5f02\u7ef4A\u9178 | 4759-48-2 | \u745e\u5a01\u5c14\u751f\u7269\u79d1\u6280"},"content":{"rendered":"\n
\u4e2d\u6587\u540d<\/td>\u5f02\u7ef4A\u9178<\/td><\/tr>
\u4e2d\u6587\u540c\u4e49<\/td>\u7ef4A\u9178(\u7ef4\u7532\u9178);13-\u987a\u5f0f\u89c6\u9ec4\u9178;13-\u987a\u7ef4\u751f\u7d20A\u9178;\u4fdd\u80a4\u7075;\u5f02\u7ef4\u7532\u9178;\u6807\u51c6\u54c1;\u5f02\u66f2\u66ff\u916f;\u5f02\u7ef4A\u9178\u539f\u6599\u836f<\/td><\/tr>
\u82f1\u6587\u540d<\/td>Isotretinoin<\/td><\/tr>
\u82f1\u6587\u540c\u4e49<\/td>Tretinoin Impurity 1\uff08Tretinoin EP Impurity A\uff09;Anti Acne Powerful Isotretinoin Powder Isotretinoin Pharmaceutical Raw Materials;Isotretinoin Capsules;Isotretinoin-D5\/13-cis-Retinoic acid-D5;Roaccutan;(2Z,4E,6E,8E)-3,7-diMethyl-9-(2,6,6-triMethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid;ISOTRETINON;A different diMension acid<\/td><\/tr>
CAS<\/td>4759-48-2<\/strong><\/td><\/tr>
\u5206\u5b50\u5f0f<\/td>C20H28O2<\/td><\/tr>
\u5206\u5b50\u91cf<\/td>300.44<\/td><\/tr>
EINECS<\/td>225-296-0<\/td><\/tr>
\u7ed3\u6784\u5f0f<\/td>\"\u5f02\u7ef4A\u9178\"<\/td><\/tr>
\u6027\u8d28<\/td><\/tr>
\u7194\u70b9<\/td>172-175 \u00b0C(lit.)<\/td><\/tr>
\u6cb8\u70b9<\/td>381.66\u00b0C (rough estimate)<\/td><\/tr>
\u5bc6\u5ea6<\/td>1.0597 (rough estimate)<\/td><\/tr>
\u6298\u5c04\u7387<\/td>1.4800 (estimate)<\/td><\/tr>
\u50a8\u5b58\u6761\u4ef6<\/td>\u221220\u00b0C<\/td><\/tr>
\u6eb6\u89e3\u5ea6<\/td>Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions.<\/td><\/tr>
\u9178\u5ea6\u7cfb\u6570(pKa)<\/td>4.76\u00b10.33(Predicted)<\/td><\/tr>
\u5f62\u6001<\/td>Fine Crystalline Powder<\/td><\/tr>
\u989c\u8272<\/td>Yellow-orange to orange<\/td><\/tr>
\u6c34\u6eb6\u89e3\u6027<\/td>insoluble<\/td><\/tr>
\u6700\u5927\u6ce2\u957f(\u03bbmax)<\/td>354nm(EtOH)(lit.)<\/td><\/tr>
Merck<\/td>14,5228<\/td><\/tr>
\u7a33\u5b9a\u6027<\/td>Stable, but probably air and light sensitive. Combustible. Incompatible with strong oxidizing agents.<\/td><\/tr>
InChIKey<\/td>SHGAZHPCJJPHSC-YCNIQYBTSA-N<\/td><\/tr>
EPA\u5316\u5b66\u7269\u8d28\u4fe1\u606f<\/td>Isotretinoin (4759-48-2)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

\u672c\u516c\u53f8\u7684\u6240\u6709\u4ea7\u54c1\u4ec5\u7528\u4e8e\u79d1\u5b66\u7814\u7a76\u6216\u8005\u5de5\u4e1a\u5e94\u7528\u7b49\u975e\u533b\u7597\u76ee\u7684\uff0c\u4e0d\u53ef\u7528\u4e8e\u4eba\u7c7b\u6216\u52a8\u7269\u7684\u4e34\u5e8a\u8bca\u65ad\u6216\u6cbb\u7597\uff0c\u975e\u836f\u7528\uff0c\u975e\u98df\u7528\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u4e2d\u6587\u540d \u5f02\u7ef4A\u9178 \u4e2d\u6587\u540c\u4e49 \u7ef4A\u9178(\u7ef4\u7532\u9178);13-\u987a\u5f0f\u89c6\u9ec4\u9178;13-\u987a\u7ef4\u751f\u7d20A\u9178;\u4fdd\u80a4\u7075;\u5f02\u7ef4\u7532\u9178;\u6807\u51c6\u54c1; […]<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-589","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/589","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=589"}],"version-history":[{"count":1,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/589\/revisions"}],"predecessor-version":[{"id":590,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/589\/revisions\/590"}],"wp:attachment":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=589"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=589"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=589"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}