{"id":882,"date":"2023-02-01T09:34:36","date_gmt":"2023-02-01T01:34:36","guid":{"rendered":"https:\/\/app.lemaidi888.com\/?p=882"},"modified":"2023-02-01T09:34:37","modified_gmt":"2023-02-01T01:34:37","slug":"%e4%b9%99%e8%83%ba%e5%98%a7%e5%95%b6-58-14-0-%e7%91%9e%e5%a8%81%e5%b0%94%e7%94%9f%e7%89%a9%e7%a7%91%e6%8a%80","status":"publish","type":"post","link":"https:\/\/app.lemaidi888.com\/?p=882","title":{"rendered":"\u4e59\u80fa\u5627\u5576 | 58-14-0 | \u745e\u5a01\u5c14\u751f\u7269\u79d1\u6280"},"content":{"rendered":"\n
\u4e2d\u6587\u540d<\/td>\u4e59\u80fa\u5627\u5576<\/td><\/tr>
\u4e2d\u6587\u540c\u4e49<\/td>6-\u4e59\u57fa-5-(4-\u6c2f\u82ef\u57fa)-2,4-\u5627\u5576\u4e8c\u80fa;2,4-\u4e8c\u6c28\u57fa-6-\u4e59\u57fa-5-\u5bf9\u6c2f\u82ef\u57fa\u5627\u5576;\u6bd4\u5229\u7f8e\u80fa;\u8fbe\u62c9\u5339\u6797;\u4e59\u80fa\u5627\u5576;\u606f\u759f\u5b9a;\u4e59\u5627\u5576,\u606f\u759f\u5b9a;\u9a6c\u6765\u9170\u4e9a\u80fa-\u7fa7\u9178<\/td><\/tr>
\u82f1\u6587\u540d<\/td>Pyrimethamine<\/td><\/tr>
\u82f1\u6587\u540c\u4e49<\/td>2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine;[2-amino-5-(4-chlorophenyl)-6-ethyl-pyrimidin-4-yl]amine;Pyrimethamine,5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine;Pyrimethamine (200 mg);PyriMethaMine,darapriM;5-(p-chlorophenyl)-6-ethyl-4-pyrimidinediamine;BW 50-63;bw50-63<\/td><\/tr>
CAS<\/td>58-14-0<\/strong><\/td><\/tr>
\u5206\u5b50\u5f0f<\/td>C12H13ClN4<\/td><\/tr>
\u5206\u5b50\u91cf<\/td>248.71<\/td><\/tr>
EINECS<\/td>200-364-2<\/td><\/tr>
\u7ed3\u6784\u5f0f<\/td>\"\u4e59\u80fa\u5627\u5576\"<\/td><\/tr>
\u6027\u8d28<\/td><\/tr>
\u7194\u70b9<\/td>233-234\u00b0C<\/td><\/tr>
\u6cb8\u70b9<\/td>393.35\u00b0C (rough estimate)<\/td><\/tr>
\u5bc6\u5ea6<\/td>1.2171 (rough estimate)<\/td><\/tr>
\u6298\u5c04\u7387<\/td>1.6110 (estimate)<\/td><\/tr>
\u50a8\u5b58\u6761\u4ef6<\/td>0-6\u00b0C<\/td><\/tr>
\u6eb6\u89e3\u5ea6<\/td>Prepare the solution immediately before use. Dissolve 0.25 g in a mixture of 1 volume of methanol R and 3 volumes of methylene chloride R and dilute to 10 mL with the same mixture of solvents. The solution is clear (2.2.1) and not more intensely coloured than reference solution BY6 (2.2.2, Method II).<\/td><\/tr>
\u9178\u5ea6\u7cfb\u6570(pKa)<\/td>pKa 7(t=20.0) (Uncertain)<\/td><\/tr>
\u5f62\u6001<\/td>neat<\/td><\/tr>
\u6c34\u6eb6\u89e3\u6027<\/td><0.01 g\/100 mL at 21 \u00baC<\/td><\/tr>
\u6700\u5927\u6ce2\u957f(\u03bbmax)<\/td>276nm(lit.)<\/td><\/tr>
Merck<\/td>14,7985<\/td><\/tr>
BRN<\/td>219864<\/td><\/tr>
\u7a33\u5b9a\u6027<\/td>Stable, but light sensitive. Combustible. Incompatible with strong oxidizing agents.<\/td><\/tr>
NIST\u5316\u5b66\u7269\u8d28\u4fe1\u606f<\/td>Pyrimethamine(58-14-0)<\/td><\/tr>
(IARC)\u81f4\u764c\u7269\u5206\u7c7b<\/td>3 (Vol. 13, Sup 7) 1987<\/td><\/tr>
EPA\u5316\u5b66\u7269\u8d28\u4fe1\u606f<\/td>Pyrimethamine (58-14-0)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

\u672c\u516c\u53f8\u7684\u6240\u6709\u4ea7\u54c1\u4ec5\u7528\u4e8e\u79d1\u5b66\u7814\u7a76\u6216\u8005\u5de5\u4e1a\u5e94\u7528\u7b49\u975e\u533b\u7597\u76ee\u7684\uff0c\u4e0d\u53ef\u7528\u4e8e\u4eba\u7c7b\u6216\u52a8\u7269\u7684\u4e34\u5e8a\u8bca\u65ad\u6216\u6cbb\u7597\uff0c\u975e\u836f\u7528\uff0c\u975e\u98df\u7528\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u4e2d\u6587\u540d \u4e59\u80fa\u5627\u5576 \u4e2d\u6587\u540c\u4e49 6-\u4e59\u57fa-5-(4-\u6c2f\u82ef\u57fa)-2,4-\u5627\u5576\u4e8c\u80fa;2,4-\u4e8c\u6c28\u57fa-6-\u4e59\u57fa-5-\u5bf9\u6c2f […]<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-882","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/882","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=882"}],"version-history":[{"count":1,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/882\/revisions"}],"predecessor-version":[{"id":883,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=\/wp\/v2\/posts\/882\/revisions\/883"}],"wp:attachment":[{"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=882"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=882"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/app.lemaidi888.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=882"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}