中文名 | 异维A酸 |
中文同义 | 维A酸(维甲酸);13-顺式视黄酸;13-顺维生素A酸;保肤灵;异维甲酸;标准品;异曲替酯;异维A酸原料药 |
英文名 | Isotretinoin |
英文同义 | Tretinoin Impurity 1(Tretinoin EP Impurity A);Anti Acne Powerful Isotretinoin Powder Isotretinoin Pharmaceutical Raw Materials;Isotretinoin Capsules;Isotretinoin-D5/13-cis-Retinoic acid-D5;Roaccutan;(2Z,4E,6E,8E)-3,7-diMethyl-9-(2,6,6-triMethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid;ISOTRETINON;A different diMension acid |
CAS | 4759-48-2 |
分子式 | C20H28O2 |
分子量 | 300.44 |
EINECS | 225-296-0 |
结构式 | ![]() |
性质 | |
熔点 | 172-175 °C(lit.) |
沸点 | 381.66°C (rough estimate) |
密度 | 1.0597 (rough estimate) |
折射率 | 1.4800 (estimate) |
储存条件 | −20°C |
溶解度 | Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions. |
酸度系数(pKa) | 4.76±0.33(Predicted) |
形态 | Fine Crystalline Powder |
颜色 | Yellow-orange to orange |
水溶解性 | insoluble |
最大波长(λmax) | 354nm(EtOH)(lit.) |
Merck | 14,5228 |
稳定性 | Stable, but probably air and light sensitive. Combustible. Incompatible with strong oxidizing agents. |
InChIKey | SHGAZHPCJJPHSC-YCNIQYBTSA-N |
EPA化学物质信息 | Isotretinoin (4759-48-2) |
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