| 中文名 | 乙胺嘧啶 |
| 中文同义 | 6-乙基-5-(4-氯苯基)-2,4-嘧啶二胺;2,4-二氨基-6-乙基-5-对氯苯基嘧啶;比利美胺;达拉匹林;乙胺嘧啶;息疟定;乙嘧啶,息疟定;马来酰亚胺-羧酸 |
| 英文名 | Pyrimethamine |
| 英文同义 | 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine;[2-amino-5-(4-chlorophenyl)-6-ethyl-pyrimidin-4-yl]amine;Pyrimethamine,5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine;Pyrimethamine (200 mg);PyriMethaMine,darapriM;5-(p-chlorophenyl)-6-ethyl-4-pyrimidinediamine;BW 50-63;bw50-63 |
| CAS | 58-14-0 |
| 分子式 | C12H13ClN4 |
| 分子量 | 248.71 |
| EINECS | 200-364-2 |
| 结构式 |  |
| 性质 | |
| 熔点 | 233-234°C |
| 沸点 | 393.35°C (rough estimate) |
| 密度 | 1.2171 (rough estimate) |
| 折射率 | 1.6110 (estimate) |
| 储存条件 | 0-6°C |
| 溶解度 | Prepare the solution immediately before use. Dissolve 0.25 g in a mixture of 1 volume of methanol R and 3 volumes of methylene chloride R and dilute to 10 mL with the same mixture of solvents. The solution is clear (2.2.1) and not more intensely coloured than reference solution BY6 (2.2.2, Method II). |
| 酸度系数(pKa) | pKa 7(t=20.0) (Uncertain) |
| 形态 | neat |
| 水溶解性 | <0.01 g/100 mL at 21 ºC |
| 最大波长(λmax) | 276nm(lit.) |
| Merck | 14,7985 |
| BRN | 219864 |
| 稳定性 | Stable, but light sensitive. Combustible. Incompatible with strong oxidizing agents. |
| NIST化学物质信息 | Pyrimethamine(58-14-0) |
| (IARC)致癌物分类 | 3 (Vol. 13, Sup 7) 1987 |
| EPA化学物质信息 | Pyrimethamine (58-14-0) |
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